Immune system disorders in dogs is are a serious problem. When this disorder afflicts your dog, the immune system can no longer do its job of protecting your dog’s health. In some cases, the immune system starts attacking healthy cells, and this leads to serious complications. 

Talk to your vet immediately if you notice any abnormal symptoms or suspect your dog has immune system issues. Such disorders can lead to disability or even death.

Autoimmune Hemolytic Anemia

This condition happens when the immune system mistakes red blood cells for foreign bodies and starts attacking them, leading to a reduction in red blood cell count. Your dog may show all the classic signs of anemia: weakness, fatigue, and loss of appetite.

Your dog’s gums may appear pale, and his eyes might have a yellowish tint. A competent veterinarian will prescribe steroids to treat this condition. There is a 50% or so mortality rate associated with this disease. So, you should call your dog’s healthcare provider immediately to save your pet’s life.  

Can Dogs Get Lupus? Yes!

Another immune system disorder that afflicts dogs is lupus. This autoimmune disease also afflicts humans. It causes the dog’s immune system to target the joints and the skin, but this condition is rare in dogs.

The classic manifestations of this disease are joint pain and recurrent skin problems. Veterinarians mainly focus on alleviating the pain that comes with the disease because there is no cure for it.

Arthritis and Skin Disorders in Dogs

Skin and arthritis are two examples of autoimmune disorders in dogs. In the case of arthritis, the dog’s immune system attacks the dog’s joints. The symptoms of this disorder are fever and limping. Usually, the limping affects different limbs at different times.

When your dog’s immune system targets the skin, it may show signs of irritation. These include blisters and pimple-like sores. The primary treatment for this disorder is steroids. 


Experts have noticed a rise in the prevalence of immune system disorders in dogs, but the reasons for this is are unclear. Several breeds have an increased risk of this condition. Some of these dog breeds are Akitas, Great Danes, Poodles, and Dachshunds

German Shepherds and Siberian Huskies have a high risk of lupus, while Akitas and Dachshunds have an increased risk for immune system disorders that afflict the skin. 

Finally, many veterinarians suspect that the primary contributory factors for autoimmune disorders in dogs are environmental factors and genetics. In some cases, diet may be a factor.

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